Tablets, chewable tablets, oral suspension
To treat a variety of bacterial infections, including those of the sinuses and middle ear, skin and soft tissues, genitourinary tract, and the respiratory tract. The medication is effective only against infections caused by bacteria, not against those caused by viruses, fungi, or other microorganisms.
Amoxicillin blocks the formation of bacterial cell walls, rendering bacteria unable to multiply and spread. Clavulanate enhances the effectiveness of amoxicillin by inhibiting the activity of a specific enzyme (beta-lactamase) produced by certain drug-resistant strains of bacteria.
Tablets-- Adults and children more than 88 lbs: 250 to 500 mg of amoxicillin with 125 mg of clavulanate every eight hours. Children up to 88 lbs: 6.7 to 13.3 mg of amoxicillin with 1.7 to 3.3 mg of clavulanate per 2.2 lbs (1 kg) of body weight every eight hours. Chewable tablets and oral suspension-- Adults and children more than 88 lbs: 250 to 500 mg of amoxicillin with 62.5 to 125 mg of clavulanate every eight hours. Children up to 88 lbs: 6.7 to 13.3 mg of amoxicillin with 1.7 to 3.3 mg of clavulanate per 2.2 lbs (1 kg) of body weight every 8 hours. Newer dosage for adults: 875 mg of amoxicillin with 125 mg of clavulanate twice a day.
One to two hours.
Six to eight hours.
Best taken on an empty stomach, but may be taken with food to minimize stomach irritation or diarrhea.
Store in a tightly sealed container away from heat and direct light. Keep the liquid form refrigerated, but do not allow it to freeze.
Take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and take the next one. Do not double the next dose.
Take this medication as prescribed for the full treatment period, even if you begin to feel better before the scheduled end of therapy.
Prolonged use can make you more susceptible to bacterial or fungal infections (such as yeast infections).
No special problems are expected.
Do not drive or engage in hazardous work until you determine how the medicine affects you.
No special precautions are necessary.
Limited studies have found no evidence of birth defects. Consult your doctor if you are pregnant or plan to become pregnant.
Amoxicillin/clavulanate may pass into breast milk and cause problems in the nursing infant; avoid use while breast feeding.
No special problems are expected.
Those who are prone to asthma, hay fever, hives, or allergies may be more likely to have an allergic reaction to a penicillin antibiotic. If severe diarrhea occurs as a side effect of this drug, do not take antidiarrheal medications; call your doctor for advice instead. This drug can cause false results on some urine sugar tests for patients who have diabetes.
Severe diarrhea, nausea, unusual excitability, seizures, or vomiting.
Call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.
Consult your doctor for advice if you are taking erythromycins, disulfiram, anticoagulants, tetracyclines, oral contraceptives, or gout drugs.
None expected.
Consult your doctor if you have a history of allergies, asthma, congestive heart failure, gastrointestinal disorders (especially colitis associated with the use of antibiotics), or impaired kidney function.
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